姓名 | 周春華 | 性別 | 男 | |
職稱 | 副主任醫師 | |||
研究方向 | 1.急、慢性胰腺炎(自身免疫性胰腺炎)基礎研究和臨床研究 2. 超聲內鏡臨床診療及轉化研究 3.醫工交叉 | |||
電子郵箱 | zhou_chunh@163.com | |||
個人簡介 | 周春華,男,中共黨員,醫學博士,上海交通大學醫恒达附屬瑞金醫院消化科副主任、副主任醫師,碩士研究生導師,目前主持國家自然科學基金面上項目、青年項目各1項,參與國家自然科學基金面上項目、上海市科委課題、研究者發起的臨床研究多項課題。現任中華醫學會第12屆消化病分會青年委員、設備研發協作組委員、中華醫學會消化內鏡分會設備研發協作組委員,中國抗癌協會胰腺腫瘤專業委員會委員,上海市第12屆消化病分會青年委員會副組長、胰腺病學組副組長、上海市消化內鏡分會超聲內鏡學組委員,海峽兩岸醫藥衛生交流協會消化病學會分會青年委員。臨床業務:消化系統常見疾病、多發病診治,專攻膽道胰腺疾病診療,包括超聲內鏡(EUS-FNA)和ERCP對膽道胰腺疾病的診治;消化道早癌、黏膜下腫瘤內鏡治療(ESD)。發表SCI收錄論文30余篇,中文論文20余篇。 | |||
主要成果 | 近三年發表英文論文: 1. Juanhui Lin, Yuansong Wei, Xiaxian Gu, Miaoru Liu, Mengru Wang, Renxiang Zhou, Duowu Zou, Lichen Yin, Chunhua Zhou, Duanmin Hu. Nanotherapeutics-mediated restoration of pancreatic homeostasis and intestinal barrier for the treatment of severe acute pancreatitis. J Control Release. 2025 Jan 10:377:93-105 共同通訊作者 2. Chunhua Zhou, Jiawei Geng, Hanyi Huang, Lintao Dan, Zhipeng Wu, Xixian Ruan, Yao Zhang, Jie Chen, Jing Sun, Duowu Zou. Adherence to the Mediterranean diet is associated with reduced chronic pancreatitis risk: a longitudinal cohort study. Food Funct. 2024 Nov 11;15(22):11072-11082. 第一作者 3. Xianzheng Qin, Taojing Ran, Benyan Zhang, Chunhua Zhou, Duowu Zou. An unusual case of duodenal neuroendocrine tumor presenting with melena diagnosed by EUS-guided fine-needle biopsy. Endoscopic Ultrasound. 2024 13(3):190-192 共同通訊作者 4. Yaya Bai, Xianzheng Qin, Xiang Ao, Taojing Ran, Chunhua Zhou, Duowu Zou. The role of EUS in the diagnosis of early chronic pancreatitis. Endoscopic Ultrasound.2024. 13(4):232-238 共同通訊作者 5. Kui Wang, Xianzheng Qin, Taojing Ran, Yundi Pan, Yu Hong, Jiawei Wang, Xianda Zhang, XiaoNan Shen, Chenxiao Liu, Xinchen Lu, Yifei Chen, Yaya Bai, Yao Zhang, , Duowu Zou. Causal link between gut microbiota and four types of pancre Chunhua Zhou atitis: a genetic association and bidirectional Mendelian randomization study. Frontiers in microbiology.2023, 23:14:1290202. 共同通訊作者 6. Kui Wang, Suijian Wang, Xianzheng Qin, Yifei Chen, Yuhua Chen, Jiawei Wang, Yao Zhang, Qiang Guo, Chunhua Zhou, Duowu Zou. The causal relationship between gut microbiota and biliary tract cancer: comprehensive bidirectional Mendelian randomization analysis. Front Cell Infect Microbiol. 2024 Mar 15:14:1308742. 共同通訊作者 7. Kui Wang, Suijian Wang, Yuhua Chen, Xinchen Lu, Danshu Wang, Yao Zhang , Wei Pan, Chunhua Zhou, Duowu Zou. Causal relationship between gut microbiota and risk of gastroesophageal reflux disease: a genetic correlation and bidirectional Mendelian randomization study. Front Immunol. 2024 Feb 21:15:1327503. 共同通訊作者 8. Yao Zhang, Jiaxin Wang, Hongxiang Sun, Zhenzhen Xun, Zirui He, Yizhou Zhao, Jingjing Qi, Sishen Sun, Qidi Yang, Yubei Gu, Ling Zhang, Chunhua Zhou, Youqiong Ye, Ningbo Wu, Duowu Zou, Bing Su. TWIST1+FAP+ fibroblasts in the pathogenesis of intestinal fibrosis in Crohn's disease. J Clin Invest. 2024 Jul 18;134(18):e179472. 共同作者 9. Xianzheng Qin, Taojing Ran, Yifei Chen, Yao Zhang, Dong Wang, Chunhua Zhou, Duowu Zou. Artificial Intelligence in Endoscopic Ultrasonography-Guided Fine-Needle Aspiration/Biopsy (EUS-FNA/B) for Solid Pancreatic Lesions: Opportunities and Challenges.Diagnostics 2023, 13(19), 3054; DOI: 10.3390/diagnostics13193054 共同通訊作者 10. Xianzheng Qin, Minmin Zhang, Chunhua Zhou, Taojing Ran, Yundi Pan, Yingjiao Deng, Xingran Xie, Yao Zhang, Tingting Gong, Benyan Zhang, Ling Zhang, Yan Wang, Qingli Li, Dong Wang, Lili Gao, Duowu Zou. A deep learning model using hyperspectral image for EUS-FNA cytology diagnosis in pancreatic ductal adenocarcinoma. Cancer Med. 2023 Aug;12(16):17005-17017. 共同第一作者 11. Xian-Da Zhang, Ling Zhang, Ting-Ting Gong, Zhuo-Ran Wang, Kang-Li Gu, Jun Li, Yuan Chen, Jian-Tao Zhang, Ben-Gong Ye, Jin Ding, Jian-Wei Zhu, Feng Liu, Duan-Min Hu, JianGang Chen, Chun-Hua Zhou, Duo-Wu Zou. A combined radiomic model distinguishing GISTs from leiomyomas and schwannomas in the stomach based on endoscopic ultrasonography images. J Appl Clin Med Phys. 2023 Jul;24(7):e14023. 共同通訊作者 12. Xian-Da Zhang, Yao Zhang, Yi-Zhou Zhao, Chun-Hua Zhou, Duo-Wu Zou. Autoimmune pancreatitis: A bibliometric analysis from 2002 to 2022. Front Immunol. 2023 Feb 22;14:1135096. 共同通訊作者 13. Xian Zheng Qin, Chun Hua Zhou, Ben Yan Zhang, Ling Zhang, Ting Ting Gong, Min Min Zhang, Dong Wang, Duo Wu Zou. Recurrent acute pancreatitis caused by duodenal papillary adenoma: A case report and literature review. J Dig Dis. 2023 Jan;24(1):60-66. 共同作者 14. Jia Jia Xu, Yu Ting Meng, Wen Bin Zou, Jiu Long Zhao, Xue Fang, Yao Zhang, Wei Zhou, Ling Zhang, Kai Xuan Wang, Liang Hao Hu, Zhuan Liao, Chun Hua Zhou, Duo Wu Zou. Cross-sectional evaluation of gut microbial-host co-metabolites in patients with chronic pancreatitis. J Dig Dis. 2023 Feb 16. 共同通訊作者 15. Jinfeng Li, Chunhua Zhou, Jing Zhang, Fei Xu, Yuting Zheng, Shige Wang, Duowu Zou. Photo-induced tumor therapy using MnO2/IrO2-PVP nano-enzyme with TME-responsive behaviors. Colloids Surf B Biointerfaces. 2021 Sep: 205:111852. 共同第一作者 16. Chunhua Zhou, Yao Zhang, Feihu Yan, Yizhou Zhao, Shige Wang, Bingqian Guo, Jia He, Duowu Zou. Vapor deposition synthesis of polypyrrole nanoparticles with a tunable photothermal conversion capacity. Colloids and Surfaces A: Physicochemical and Engineering Aspects,2021, 613,126073 17. Xiaonan Shen#, Chunhua Zhou, Haoran Feng, Jialu Li, Tianxue Xia, Xi Cheng, Ren Zhao, Duowu Zou. ETV1 Positively Correlated With Immune Infiltration and Poor Clinical Prognosis in Colorectal Cancer. Front Immunol. 2022 Jul 4;13:939806. 共同第一作者 近五年主持課題: 1. 腸道間質細胞通過R-spondin3-Wnt通路調控腸Lgr5+幹細胞在重症急性胰腺炎腸上皮屏障功能維護中的機製研究,52萬,在研,2023-2026 國家自然科學基金(面上項目),主持 2. IL-22激活IL-22R1/STAT3通路調控腸Lgr5+幹細胞增殖參與損傷腸上皮修復在重症急性胰腺炎合並腸屏障功能障礙中的機製研究,22萬,結題,2019-2021 國家自然科學基金(青年項目),主持 3. IL-22在調控SAP伴腸屏障功能障礙中的機製研究,3萬,結題,2019/01-2020/12 江蘇省高校自然科學研究項目(面上項目),主持 4. 膽汁酸激活TGR5-EGFR-ERK1/2途徑調控胃Lgr5+細胞分化參與反流性胃炎發病的機製研究,25萬,結題,2016/01-2021/01,江蘇省青年醫學重點人才項目,主持 5. 儀實驗室樣機研發, 地區級,10萬,在研,2023/10 - 2026-10,上海交通大學-上海理工大學醫工交叉合作項目,主持 6. IBD精準體系的開發與驗證, 160萬(本中心4.8萬),在研,2023/12- 2026/12,國家重點研發計劃,課題骨幹 近三年專利: 1. 一種活檢穿刺標本處理操作平臺, 實用新型,2023/06,ZL 2022 2 2563344.6 第一發明人 2. 基於高光譜成像技術的穿刺樣本病理分析系統及方法,發明專利,2024/05/03 ZL 2022 1 0863506.X,第六發明人 3. 一種內鏡操作護理盤及其使用方法,發明專利,2024/08/13,ZL 2021 1 0638703.7,第三發明人 4. 一種玻片順序化染色裝置, 實用新型,2022/08 ,ZL 2021 2 2990666.4, 第二發明人 5. 一種快速染色裝置, 實用新型,2022/08,ZL 2021 2 2988851.X 第二發明人 6. 一種染缸可旋轉的自動染色風幹裝置, 實用新型,2022/08,ZL 2021 2 2901292.4,第二發明人 7. 一種鼻膽管口鼻交換裝置, 實用新型,2023/08 ,ZL 2022 2 3084412.7,第三發明人 |